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Upper limb reflex sympathetic dystrophy associated with occult malignancy

A Ku1, E Lachmann, R Tunkel

  • 1Rehabilitation Medicine, New York Hospital-Cornell Medical Center, New York, USA.

Archives of Physical Medicine and Rehabilitation
|July 1, 1996
PubMed
Summary
This summary is machine-generated.

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Reflex sympathetic dystrophy (RSD) in cancer survivors may signal occult malignancy. Prompt diagnosis and treatment of the underlying tumor are crucial for symptom improvement and avoiding prolonged medical interventions.

Area of Science:

  • Oncology
  • Neurology
  • Pain Management

Background:

  • Reflex sympathetic dystrophy (RSD) is a complex regional pain syndrome.
  • RSD is rarely associated with occult malignancy.
  • Cancer survivors in remission may develop unexplained RSD symptoms.

Observation:

  • Two cases of RSD in patients with a history of cancer are presented.
  • Both patients experienced persistent symptoms despite physical therapy.
  • Initial workup revealed localized masses indicative of recurrent or new malignancy.

Findings:

  • Recurrent breast carcinoma was diagnosed in the first patient with an apical lung mass.
  • Lymphoma, a second primary malignancy, was found in the second patient with an axillary mass.
  • Medical treatment of the underlying tumors led to improved limb function in both cases.

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Implications:

  • Spontaneous RSD in cancer survivors warrants investigation for occult malignancy.
  • Early detection and treatment of recurrent or new cancers can improve patient outcomes.
  • Failure to suspect malignancy may lead to delayed diagnosis and unnecessary procedures.