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Background pregnancy rates in an infertile population
N Gleicher1, B VanderLaan, D Pratt
1Center for Human Reproduction and the Foundation for Reproductive Medicine and Blue Cross Blue Shield of Illinois, Chicago, IL, USA.
Human Reproduction (Oxford, England)
|May 1, 1996
Summary
Infertile couples have a low spontaneous pregnancy rate of 2.02% per month, accumulating to 19.9% over 12 months. This background pregnancy rate is significant for evaluating infertility treatments.
Area of Science:
- Reproductive Medicine
- Human Reproduction
- Clinical Cohort Studies
Background:
- Infertility affects a significant portion of couples seeking reproductive assistance.
- Understanding spontaneous pregnancy rates is crucial for assessing treatment efficacy.
Purpose of the Study:
- To accurately determine the spontaneous background pregnancy rate in couples experiencing infertility.
- To provide a baseline for evaluating the success of assisted reproductive technologies.
Main Methods:
- A cohort study design was employed.
- Data from 9079 treatment months were analyzed from infertile couples with at least one year of infertility.
- Pregnancy rates were calculated per inactive treatment month.
Main Results:
- The spontaneous clinical pregnancy rate was 2.02% per inactive treatment month.
- A cumulative spontaneous pregnancy rate of 19.9% was observed after 12 months.
- This indicates a notable background conception rate in the studied population.
Conclusions:
- Infertile couples possess a low, yet significant, spontaneous background pregnancy rate.
- This rate must be considered when evaluating the effectiveness of various infertility treatment modalities.
- The findings support the need for individualized treatment plans in reproductive medicine.