Related Experiment Video
Updated: Aug 29, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
[Drug advertising in medical journals]
R Madridejos1, C Cabezas, F Flor
1CAP Just Oliveras, L'Hospitalet de Llobregat, Barcelona.
Objective:
To find the percentage of pages of advertising in 6 Spanish medical journals and compare their principal features with the criteria of the international committee of editors of medical journals.
Design:
A descriptive crossover study.
Setting:
The Spanish general medical journals with the highest circulation.
Participants:
All the issues of journals published between January and March 1993 (n = 56) were selected in order to calculate the average percentage of advertising. To analyse the adverts, all the adverts in 32 issues (n = 657) were selected by means of stratified random sampling of journals from the period July 1992 to June 1993.
Results:
The average number of advertising pages was 39.16%. 7.8% were publicity articles with or without an advertisement. Adverts filled the best pages of the journals. In 11.7% of cases the adverts were connected with articles in the journal; in 23.9% they were inserted within article. 13.4% of the adverts analysed were for drug products with doubtful or nil intrinsic value; and 34.5% were pharmaceutical novelties (marketed after 1991). The therapeutic groups with most advertisements were ACE inhibitors (13.2%), analgesics (7.8%), calcium antagonists (7.2%) and AINE (7.2%). Paracetamol (6.1%) was the active principal advertised most often.
Conclusion:
The percentage of advertising seems excessive in all the journals except one and very much above the non-advertising informative material. There should be improvement by bringing journals into line with international editorial criteria.
Related Concept Videos
Clinical Trials
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Drug Regulation
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and anaphylaxis:...
Cardiovascular Drugs: Classification based on Therapeutic Indications

