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Ifosfamide-induced nonconvulsive status epilepticus

A Bhardwaj1, P S Badesha

  • 1Veterans Affairs Medical Center, Dayton, OH 45428, USA.

The Annals of Pharmacotherapy
|December 1, 1995
PubMed
Summary
This summary is machine-generated.

Ifosfamide can cause nonconvulsive status epilepticus, a rare central nervous system toxicity. This case report details a patient who developed this condition after ifosfamide treatment for recurrent cancer.

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Area of Science:

  • Oncology
  • Neurology
  • Pharmacology

Background:

  • Ifosfamide is a chemotherapy agent with known central nervous system (CNS) toxicity.
  • CNS toxicities from ifosfamide, such as seizures, are more commonly reported in pediatric patients.
  • Nonconvulsive status epilepticus (NCSE) is a prolonged seizure state without obvious convulsive activity.