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[Increased serum level of c-erbB-2-coded protein p105 in patients with pre-eclampsia]
Gynakologisch-Geburtshilfliche Rundschau
|January 1, 1995
Abstract
Objective:
This study investigated p105 serum levels in normal pregnancies and in preeclamptic women.
Patients And Methods:
The p105 serum level was determined in 65 women with normal pregnancy and 25 preeclamptic women.
Results:
The mean p105 serum level for the control group was 102-333 fmol/ml (median 163 fmol/ml). Preeclamptic women had significant higher serum levels (97-368 fmol/ml, median 202 fmol/ml, p < 0,005).
Conclusion:
Elevated serum levels of the c-erbB-2-encoded protein p105 in preeclamptic women could be the result of endothelial dysfunction in preeclampsia.