[Medical and biological aspects of the dioxin problem]

The article deals with the problem of dioxidine and similar chemicals influencing unfavorable ecologic situation in the world. The authors briefly describe medical and biologic aspects of the problem, demonstrating the present data accumulated mostly by foreign authors and associated primarily with experiments on animals. The information connected with humans appears to be limited, and all researchers have no universal opinion on dioxidine's degree of jeopardy for humans. Scientists of Ufa Research Center for Human Ecology and Occupational Medicine collected unique material on changes in health state of workers after the exposure to 2,4,5-T and dioxidine-related disorder as chloracne. The authors define main spheres of research on the problem.