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Immunoglobulin diversity: rearranging by cutting and repairing
1Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Current Biology : CB
|February 1, 1996
Abstract:
The recombination process that assembles antigen-receptor genes is now understood in some biochemical detail. The initial steps reflect a common theme seen in retroviral integration and prokaryotic transposition, and the later steps involve the enzymatic machinery for double-strand break DNA repair.