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[Modulation of cellular response expression during prolonged treatment with antiestrogens]
E Badia1, M J Duchesne, M Astruc
1INSERM, Unité 439, Montpellier, France.
Summary
Prolonged antiestrogen treatment can unexpectedly alter estrogen-dependent gene expression and activate AP-1 responses. These findings reveal new antiestrogen activities with potential implications for endocrine therapy.
Area of Science:
- Endocrinology
- Molecular Biology
- Cancer Research