Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Collagen network remodelling and left ventricular function in constrictive pericarditis

M Chello1, P Mastroroberto, R Romano

  • 1Department of Cardiac Surgery, Medical School of Catanzaro, Italy.

Heart (British Cardiac Society)
|February 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Black Hole Spectroscopy and Tests of General Relativity with GW250114.

Physical review letters·2026
Same author

A tailored histology-driven molecular profiling algorithm proposal for salivary gland cancers.

ESMO open·2026
Same author

GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

Physical review letters·2025
Same author

Polystyrene micro and nanoplastics: A comparative study of the cytotoxic effects exerted on Mytilus galloprovincialis gills.

Ecotoxicology and environmental safety·2025
Same author

Frequency-Dependent Squeezed Vacuum Source for the Advanced Virgo Gravitational-Wave Detector.

Physical review letters·2023
Same author

Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO's and Advanced Virgo's Third Observing Run.

Physical review letters·2022
Same journal

Feasibility of early double sequential defibrillation in out-of-hospital cardiac arrest: the double-D randomised pilot trial.

Heart (British Cardiac Society)·2026
Same journal

Correspondence on 'When a patent foramen ovale becomes pathological' by Saji and Ohara.

Heart (British Cardiac Society)·2026
Same journal

Cost-effectiveness of N-terminal pro-B-type natriuretic peptide thresholds for echocardiography referral in primary care heart failure management.

Heart (British Cardiac Society)·2026
Same journal

Optimal timing of aspirin discontinuation after acute coronary syndrome treated with percutaneous coronary intervention: a systematic review and meta-analysis.

Heart (British Cardiac Society)·2026
Same journal

Importance of rating: the impact of establishing age and sex normative values for left ventricular strain rate.

Heart (British Cardiac Society)·2026
Same journal

Man in his 40s with palpitations.

Heart (British Cardiac Society)·2026
See all related articles

Patients with constrictive pericarditis show increased myocardial collagen and trabecular thickening. These changes may impair left ventricular function, impacting cardiac performance.

Area of Science:

  • Cardiology
  • Pathology
  • Biomedical Engineering

Background:

  • Constrictive pericarditis can impair cardiac function.
  • The role of myocardial collagen changes in this condition is not fully understood.

Purpose of the Study:

  • To investigate collagen content and architecture in the myocardium of patients with constrictive pericarditis.
  • To determine if these changes correlate with left ventricular function.

Main Methods:

  • Cohort study comparing myocardial biopsy specimens from 13 constrictive pericarditis patients with 15 controls.
  • Biochemical and histological assessment of collagen (total, types I/III) and collagen meshwork.
  • Correlation with left ventricular ejection fraction and pressures.

Related Experiment Videos

Main Results:

  • Constrictive pericarditis patients had significantly higher myocardial collagen content (biochemical and histological).
  • Trabecular thickening was inversely related to left ventricular ejection fraction and deceleration time.
  • Trabecular thickening correlated with NYHA class (III/IV).

Conclusions:

  • Increased collagen content and altered architecture, particularly trabecular thickening, are present in constrictive pericarditis.
  • These myocardial changes may contribute to impaired ventricular function in this condition.