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Related Experiment Videos

Measles & malnutrition

P Bhaskaram1

  • 1National Institute of Nutrition, Hyderabad.

The Indian Journal of Medical Research
|November 1, 1995
PubMed
Summary
This summary is machine-generated.

Measles significantly impacts child nutrition, potentially causing severe deficiencies in malnourished children. Measles vaccination is crucial for prevention and safe for malnourished populations, even with co-existing tuberculosis.

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Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Nutritional Science

Background:

  • Measles is a viral infection with severe nutritional consequences for children, affecting both well-nourished and malnourished individuals.
  • Severe nutritional deficiencies like kwashiorkor/marasmus can be precipitated by measles in already malnourished children, affecting 3-4% post-infection.
  • Measles presents differently across regions; milder courses and lower mortality are observed in Asian children compared to African children, possibly due to socioeconomic factors and secondary infections.

Purpose of the Study:

  • To examine the nutritional impacts of measles in childhood.
  • To investigate the multifactorial etiology of measles-related blindness.
  • To assess the safety and efficacy of measles vaccination in malnourished children.

Main Methods:

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  • Review of existing literature on measles, nutritional status, and vaccination outcomes.
  • Analysis of measles-related complications including blindness and severe nutritional syndromes.
  • Evaluation of measles vaccine response in malnourished children and contraindications.

Main Results:

  • Measles adversely affects nutritional status, with severe deficiencies manifesting post-infection in malnourished children.
  • Measles-related blindness results from viral corneal ulceration and post-measles nutritional keratomalacia.
  • Live attenuated measles vaccine is safe and effective in malnourished children, with malnutrition and tuberculosis not being contraindications.

Conclusions:

  • Measles vaccination is the primary preventive strategy, offering significant benefits.
  • Vitamin A supplementation and antibiotic eye therapy can protect children with measles.
  • Maximizing measles vaccination coverage is essential, ensuring adequate vaccine supply and access for all susceptible children.