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Recurrent priapism as a side effect of zuclopenthixol decanoate
A M van Hemert1, W Meinhardt, D Moehadjir
1Psychiatric Hospital Bloemendaal, The Hague, The Netherlands.
Abstract:
Priapism has been described as a rare side effect of certain phenothiazine antipsychotics with high alpha1-adrenergic blocking potential. We describe a patient who in the course of clinical treatment with the thioxanthene antipsychotic zuclopenthixol (Clopixol) decanoate had several episodes of priapism. Although the alpha-blocking potential of zuclopenthixol is only moderate, it seems that in sufficient dose, or in combination with other antipsychotics, this drug is capable of inducing priapism.
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