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[Genetic counseling in psychiatric diseases]
J Körner1, M Rietschel, M M Nöthen
1Psychiatrische Klinik, Universität, Bonn.
Der Nervenarzt
|January 1, 1996
Summary
Genetic counseling for psychiatric disorders is reviewed, including empirical data for Alzheimer's and Huntington's diseases, and schizophrenia. Presymptomatic testing and teratogenic risks are discussed.
Area of Science:
- Psychiatry
- Genetics
- Medical Genetics
Context:
- Genetic counseling is crucial for psychiatric disorders.
- Empirical data and molecular genetic methods are available for specific conditions.
- Understanding genetic risks aids patient management.
Purpose:
- To review current knowledge and applications of genetic counseling in psychiatric disorders.
- To outline principles of genetic counseling for affective disorder, schizophrenia, Alzheimer's, and Huntington's disease.
- To discuss challenges in presymptomatic testing and teratogenic risks of psychopharmacological agents.
Summary:
- Genetic counseling applications for psychiatric disorders are reviewed, with available empirical data for affective disorder, schizophrenia, Alzheimer's, and Huntington's disease.
- Molecular genetic methodology is applicable to Huntington's disease and partly to Alzheimer's disease, while empirical risk figures are used for affective disorder and schizophrenia.
- The review details genetic counseling principles, presymptomatic testing issues, and teratogenic aspects of psychotropic medications during pregnancy.
Impact:
- Provides a comprehensive overview of genetic counseling in psychiatry.
- Informs clinicians and researchers about genetic risk assessment and management strategies.
- Highlights the importance of considering genetic factors and teratogenic risks in psychiatric care.