Related Experiment Videos
Familial recurrence of pulmonary sequestration
A Z Abuhamad1, T Bass, M E Katz
1Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, USA.
Obstetrics and Gynecology
|May 1, 1996
Summary
Pulmonary sequestration, a lung abnormality, is typically not familial. This report details two male infants born to the same parents with this condition, suggesting a possible genetic link.
Area of Science:
- Pediatric Surgery
- Medical Genetics
- Prenatal Diagnosis
Background:
- Pulmonary sequestration is a rare congenital lung malformation.
- It is generally considered a sporadic condition with no known familial predisposition.
Observation:
- Prenatal diagnosis of pulmonary sequestration was achieved in two consecutive pregnancies via ultrasound.
- Both fetuses were identified as male and presented with an echogenic lung mass supplied by systemic arteries.
Findings:
- Postnatal radiographic evaluation confirmed pulmonary sequestration in both male infants.
- The recurrence in siblings suggests a potential inherited component.
Implications:
- This case series challenges the notion that pulmonary sequestration is exclusively non-familial.
- It highlights the importance of considering genetic factors in recurrent cases of pulmonary sequestration.