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Castleman disease presenting as a pelvic mass
S R MacDonald1, J R Lurain, F Hoff
1Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA.
Obstetrics and Gynecology
|May 1, 1996
Summary
Giant lymph node hyperplasia, also known as Castleman disease, can mimic pelvic masses on MRI scans. This case highlights the importance of considering Castleman disease in pelvic mass evaluations.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Giant lymph node hyperplasia (Castleman disease) is a rare lymphoproliferative disorder.
- Pelvic masses can present diagnostic challenges, even with advanced imaging like MRI.
Observation:
- A postmenopausal woman presented with a rapidly enlarging uterine leiomyoma and a suspicious left adnexal mass on MRI.
- Surgical exploration revealed a solid mass in the sigmoid colon mesentery, distinct from the uterus and ovaries.
Findings:
- Histological examination confirmed the mesenteric mass as Castleman disease.
- The preoperative MRI diagnosis of an ovarian neoplasm was incorrect.
Implications:
- Castleman disease should be included in the differential diagnosis for pelvic masses.
- Accurate characterization of pelvic mass origin can be challenging despite sophisticated imaging.