Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A method for estimating an overlying layer correction in quantitative ultrasound imaging

Z F Lu1, J A Zagzebski, E L Madsen

  • 1Department of Medical Physics, University of Wisconsin-Madison 53706, USA.

Ultrasonic Imaging
|October 1, 1995
PubMed
Summary

This study introduces a novel method for quantitative ultrasound imaging to accurately compensate for signal attenuation. The technique improves backscatter estimation, enabling more consistent imaging of simulated tumors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Properties of Heavy Cosmic Nuclei Phosphorus, Chlorine, Argon, Potassium, and Calcium: Results from the Alpha Magnetic Spectrometer.

Physical review letters·2026
Same author

[Rapid determination of chlorfenapyr and its metabolites in plasma by high performance liquid chromatography-tandem mass spectrometry].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2026
Same author

[A case report of end-stage dilated cardiomyopathy caused by neutral lipid storage disease].

Zhonghua xin xue guan bing za zhi·2026
Same author

[Clinical efficacy and safety of CLAE regimen for refractory/relapsed T cell acute lymphoblastic leukemia/lymphoma: a prospective, multicenter, single-arm study].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
Same author

[Fast determination of maduramicin ammonium in serum by high performance liquid chromatography-tandem mass spectrometry].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2025
Same author

[Determination of six psychotropic drug metabolites in human plasma by LC-MS/MS method].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2025

Area of Science:

  • Medical Imaging
  • Biomedical Engineering
  • Acoustics

Background:

  • Quantitative ultrasound imaging faces challenges with attenuation losses from intervening tissue layers.
  • Accurate attenuation compensation is crucial for reliable backscatter coefficient estimation.
  • Existing methods may struggle with heterogeneous overlying tissues.

Purpose of the Study:

  • To develop and validate a new spectral-based method for compensating attenuation in quantitative ultrasound.
  • To assess the method's effectiveness in improving image consistency across different overlying layers.
  • To evaluate the accuracy of backscatter estimation after attenuation compensation.

Main Methods:

  • A novel technique involving subtraction of echo signal power spectra from uniform and reference regions was employed.

Related Experiment Videos

  • Attenuation estimation was based on changes in spectral components with frequency.
  • Phantoms with mimicking fat and muscle layers of varying irregularity were used for testing.

    • Main Results:

    • The proposed method successfully compensated for attenuation losses in phantoms with overlying layers.
    • Consistent backscatter estimator images of a simulated tumor were obtained across different phantom windows.
    • Reliable backscatter coefficient values for background material were achieved post-compensation.

    Conclusions:

    • The developed spectral subtraction method effectively compensates for attenuation in quantitative ultrasound imaging.
    • This technique enhances the accuracy and consistency of backscatter coefficient measurements.
    • The method holds promise for improved diagnostic capabilities in ultrasound-based tissue characterization.