[The effect of electrotranquilization on the hormonal indices of alcoholic patients]

The correlation between clinical signs of alcoholism dynamics and hormonal status indices was analysed in 26 patients during medical electrotranquilization sessions. Electrotranquilization (ET) was carried out by "Lénar" (Russia) apparatus. There were estimated the concentrations of the following hormones: adrenocorticotropic hormone, hydrocortisone, prolactin, follicle stimulating, luteinizing hormones, estriol, testosterone, somatotropic, thyrotropic hormones, triiodothyronine, tyrosine and insulin. The inverse correlation was observed between the estriol, testosterone and tyrosine levels on the one hand and the clinical signs of the reaction to alcohol administration on the other hand. So far as the disease severity strengthened, both the elevation of estriol and the decrease of testosterone levels were observed. The prolactin concentration correlated directly with meta-alcoholic clinical signs gravity. This confirmed the prolactin role both in postalcoholic haemostasis restoration and in pathogenesis of meta-alcoholic clinical signs. In alcoholic patients the ET normalized the serum prolactin level as well as promoted the trend to normalization of estriol and testosterone levels.