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Catecholamine-induced ductus arteriosus constriction in children

H Tomita¹, S Fuse, S Chiba

¹Department of Pediatrics, School of Medicine, Sapporo Medical University, Hokkaido, Japan.

The American Journal of Cardiology

|June 15, 1996

Summary

The smooth muscle in patent ductus arteriosus (PDA) can constrict after infancy, potentially closing the PDA later in life. Catecholamines may trigger this late closure in some patients.

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Area of Science:

Cardiovascular Science
Neonatal Physiology
Pediatric Cardiology

Background:

Patent ductus arteriosus (PDA) is a common congenital heart defect.
The ductus arteriosus typically closes shortly after birth.
Persistence of the ductus arteriosus can lead to significant hemodynamic alterations.