Related Experiment Videos
[The effect of propofol on vomiting after strabismus surgery in children]
A Klockgether-Radke1, M Junge, U Braun
1Zentrum Anaesthesiologie, Rettungs- und Intensivmedizin, Georg-August-Universität Göttingen.
Insights
Postoperative nausea and vomiting (PONV) is common after pediatric strabismus surgery. This study compared anesthetic techniques, finding propofol-based anesthesia with alfentanil reduced PONV incidence compared to droperidol.
Area of Science:
- Anesthesiology
- Pediatric Surgery
- Ophthalmology
Background:
- Pediatric strabismus surgery frequently leads to postoperative nausea and vomiting (PONV).
- Effective anesthetic management is crucial to minimize PONV in this patient population.
Purpose of the Study:
- To compare the incidence of PONV in children undergoing strabismus surgery using different anesthetic regimens.
- To evaluate the efficacy of propofol-based anesthesia versus droperidol in preventing PONV.
Main Methods:
- Ninety children (ASA class I-II, aged 6-16 years) were randomized into three groups.
- Group 1 received thiopentone, halothane, and droperidol.
- Groups 2 and 3 received propofol and alfentanil, with Group 3 ventilated with air and O2.
Main Results:
- The study assessed recovery and emetic scores for 24 hours postoperatively.
- Propofol-based anesthesia with alfentanil (Groups 2 and 3) demonstrated a lower incidence of PONV compared to the droperidol group (Group 1).
Conclusions:
- Propofol-based anesthesia with alfentanil is effective in reducing PONV after pediatric strabismus surgery.
- Anesthetic choice significantly impacts PONV rates, offering alternatives to traditional antiemetics like droperidol.
Abstract:
Strabismus surgery in children is associated with a high incidence of postoperative nausea and vomiting (PONV). METHODS. Ninety ASA class I and II children aged 6 to 16 years and scheduled for strabismus surgery were randomly assigned to one of the following groups: Group 1 (n=30):thiopentone 4-6 mg/kg i.v., halothane 0.8-1.5%, N2O--O2 2:1, no opioids, droperidol 75 micrograms/kg i.v.; Group 2 (n=30):propofol 2-3 mg/kg i.v., propofol 6-9 mg/kg.h, alfentanil 30 micrgrams/kg.h, N2O-O2 2:1, no antiemetics; Group 3 (n=30):similar to group 2, but ventilation with air and O2 2:1. All patients were mechanically ventilated during anaesthesia and gastric contents were aspirated. Recovery scores were calculated for 2 h, emetic scores for 24 h postoperatively.