Unusual appearance of intracranial fibromuscular dysplasia. A case report
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Published on: April 19, 2024
1Department of Neurosurgery, Hacettepe University School of Medicine, Ankara, Turkey.
Abstract:
Fibromuscular dysplasia (FMD) of intracranial arteries is seen rarely and usually limited to the intrapetrosal internal carotid artery or carotid siphon. The authors report a case with recurrent subarachnoid hemorrhage diagnosed angiographically as FMD with extensive involvement of intracranial arteries. Angiography showed large fusiform dilatations and multiple aneurysms along the left intracranial internal carotid artery into its major branches, middle cerebral and posterior communicating arteries, and tip of the basilar and posterior cerebral arteries. Such an angiographic appearance has not been previously reported. Radiologic findings are demonstrated and possible pathophysiologic mechanisms are discussed.
Insights
This study presents a rare case of extensive intracranial fibromuscular dysplasia (FMD) causing recurrent subarachnoid hemorrhage. The findings reveal unusual angiographic features not previously reported in FMD cases.
Area of Science:
- Neurology
- Vascular Medicine
- Radiology
Background:
- Fibromuscular dysplasia (FMD) typically affects cervical arteries, with intracranial involvement being uncommon.
- Intracranial FMD is usually confined to the internal carotid artery's intrapetrosal segment or carotid siphon.
Observation:
- A rare case of FMD involving extensive intracranial arteries is presented.
- The patient experienced recurrent subarachnoid hemorrhage.
- Angiography revealed large fusiform dilatations and multiple aneurysms.
Findings:
- The angiographic findings included widespread FMD affecting the left internal carotid artery and its major branches.
- Involvement extended to the middle cerebral, posterior communicating, basilar, and posterior cerebral arteries.
- This extensive and complex angiographic pattern is unprecedented for intracranial FMD.
Implications:
- This case expands the known spectrum of intracranial fibromuscular dysplasia.
- It highlights the importance of considering FMD in cases of unexplained subarachnoid hemorrhage with complex intracranial vascular findings.
- Further research into the pathophysiology of extensive intracranial FMD is warranted.
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