Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Chemoembolization therapy in small hepatocellular carcinoma]

H Uchida1, N Matsuo, H Sakaguchi

  • 1Department of Radiology, Nara Medical University, Japan.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|June 1, 1996
PubMed
Summary

Segmental chemoembolization using Lipiodol (Lp) mixed with anticancer agents offers a less invasive, effective treatment for small hepatocellular carcinoma (HCC). This approach shows high rates of tumor necrosis and comparable efficacy to surgery for tumors under 3 cm.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multi-centre, retrospective case series of oocyte cryopreservation in unmarried women diagnosed with haematological malignancies.

Human reproduction open·2021
Same author

Tandem Operation of a Turbo Blood Pump (BP-80-Type Centrifugal Pump) to Reduce Hemolysis.

Artificial organs·2017
Same author

A Novel Laccase Inhibitor, N-Hydroxyglycine, Produced by Penicillium citrinum YH-31.

Bioscience, biotechnology, and biochemistry·2016
Same author

Current role of hybrid CT/angiography system compared with C-arm cone beam CT for interventional oncology.

The British journal of radiology·2014
Same author

Arthroscopic partial limbectomy for labral injury of the hip: a case with a 16-year follow-up.

The Journal of bone and joint surgery. British volume·2012
Same author

A potent anti-angiogenic factor, vasohibin-1, ameliorates experimental bronchiolitis obliterans.

Transplantation proceedings·2012

Area of Science:

  • Hepatobiliary oncology
  • Interventional radiology
  • Surgical oncology

Context:

  • Hepatocellular carcinoma (HCC) is a primary liver cancer with diverse treatment options.
  • Transarterial chemoembolization (TAE) is a standard treatment for unresectable HCC.
  • Segmental therapy offers a more targeted approach than conventional TAE.

Purpose:

  • To evaluate the efficacy and safety of segmental Lipiodol (Lp)-transarterial chemoembolization (TAE) for small HCC.
  • To compare segmental Lp-TAE with surgical resection for small HCC.
  • To assess the pathological outcomes of segmental Lp-TAE.

Summary:

  • Segmental Lp-TAE, targeting tumors <2 cm within specific liver segments, involves injecting Lipiodol mixed with an anticancer agent.
  • Histopathological analysis of 15 surgically treated cases showed >80% complete necrosis in main tumors, satellite nodules, and capsular invasion areas.

Related Experiment Videos

  • Therapeutic efficacy in 51 cases with tumors <3 cm was comparable to surgical resection, with fewer complications and less patient strain.

    • Impact:

    • Segmental Lp-TAE is a promising, less invasive treatment option for small HCC, potentially becoming a frontline therapy.
    • This technique demonstrates high pathological response rates and comparable clinical outcomes to surgery.
    • Reduced complications and patient burden make segmental Lp-TAE an attractive alternative for select HCC patients.