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Related Experiment Videos

Progressive osseous heteroplasia

E S Miller1, N B Esterly, J A Fairley

  • 1Department of Dermatology, Medical College of Wisconsin, Milwaukee, USA.

Archives of Dermatology
|July 1, 1996
PubMed
Summary

Progressive osseous heteroplasia (POH) presents as early-onset cutaneous ossification in children. This rare condition involves progressive bone formation in deeper tissues, requiring awareness for accurate diagnosis.

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Area of Science:

  • Pediatric Orthopedics
  • Dermatology
  • Medical Genetics

Background:

  • Primary heterotopic ossification is rare in childhood, with known conditions like Albright hereditary osteodystrophy and fibrodysplasia ossificans progressiva.
  • Progressive osseous heteroplasia (POH) is a recently identified disorder characterized by early-onset cutaneous calcification and ossification.
  • POH is a progressive and potentially debilitating condition with initial signs appearing in infancy.