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Related Experiment Videos

The Physicians' Desk Reference. Problems and possible improvements

J S Cohen1, P A Insel

  • 1Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla, USA.

Archives of Internal Medicine
|July 8, 1996
PubMed
Summary
This summary is machine-generated.

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The Physicians' Desk Reference (PDR) provides drug information but has limitations. Its content is supplied and funded by drug makers, reflecting negotiated agreements with regulators.

Area of Science:

  • Pharmacology
  • Medical Information Dissemination

Background:

  • The Physicians' Desk Reference (PDR) is a key drug information resource for US physicians and patients.
  • The PDR's content is sourced directly from pharmaceutical manufacturers.

Purpose of the Study:

  • To critically evaluate the shortcomings of the PDR as a drug information source.
  • To examine the influence of pharmaceutical manufacturers and regulatory bodies on PDR content.

Main Methods:

  • Analysis of the PDR's content sourcing and funding model.
  • Review of the relationship between PDR information, drug package inserts, and regulatory approval processes.

Main Results:

  • PDR content is identical to drug package inserts, which are provided by pharmaceutical companies.

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  • The information presented in the PDR is a result of negotiations between commercial entities and the Food and Drug Administration (FDA).
  • Conclusions:

    • The PDR's content is inherently influenced by pharmaceutical manufacturers.
    • The PDR represents a negotiated agreement between industry and regulators, potentially impacting its objectivity.