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Related Experiment Videos

[Heart rate response to ventricular stimulation]

B Brembilla-Perrot1, S Alsagheer, D Beurrier

  • 1Service de cardiologie A, CHU Brabois, Vandoeuvre-lès-Nancy.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|February 1, 1996
PubMed
Summary

Holter monitoring of heart rate variability (HRV) aligns with changes seen after ventricular stimulation. Absence of heart rate variation post-stimulation indicates reduced HRV, suggesting a potential diagnostic correlation.

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Area of Science:

  • Cardiology
  • Autonomic Nervous System Function

Background:

  • Heart rate variability (HRV) analysis via Holter monitoring is standard for cardiac autonomic regulation assessment.
  • Rapid ventricular stimulation can alter autonomic nervous system tone.

Purpose of the Study:

  • To compare time and frequency domain HRV analysis with heart rate (HR) variations after incremental ventricular stimulation.
  • To evaluate the correlation between HRV and HR changes induced by ventricular stimulation.

Main Methods:

  • Analysis of HRV using Holter monitoring (Elatec version 3.02).
  • Incremental ventricular stimulation up to 200/min in 130 patients.
  • Comparison of time-domain (SDNN, CV, pNN50) and frequency-domain HRV parameters.

Main Results:

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  • Ventricular stimulation induced significant HR variations (>10%) in 80 patients, but not in 50.
  • Holter HRV analysis showed concordance with HR variation findings.
  • Reduced HRV parameters (SDNN, CV, pNN50, low/high frequencies) were observed in patients without HR variation post-stimulation.

Conclusions:

  • Disappearance of HR changes after ventricular stimulation correlates with absent HRV on Holter recordings.
  • This simple test is reproducible and unaffected by arrhythmias or recording quality issues.
  • The findings suggest a potential systematic application during electrophysiological investigations.