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Published on: April 8, 2018
Complete revascularization with three or more arterial conduits
A M Calafiore1, G Di Giammarco
1Division of Cardiac Surgery, University of Chieti, Italy.
Insights
Complete arterial revascularization using multiple grafts offers excellent long-term outcomes. This strategy demonstrates improved event-free survival compared to traditional methods, with low mortality rates.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery
- Vascular Surgery
Background:
- Coronary artery disease necessitates effective revascularization strategies.
- Optimizing graft choice and number is crucial for long-term patient outcomes.
Purpose of the Study:
- To evaluate the feasibility and mid-term results of complete arterial revascularization using three or more arterial conduits.
- To compare event-free survival rates between total arterial grafts and conventional mixed grafts.
Main Methods:
- Surgical technique involved using skeletonized bilateral internal thoracic arteries (ITAs) and the right gastroepiploic artery, supplemented by radial or inferior epigastric arteries as needed.
- A cohort of 247 patients received complete arterial revascularization between October 1991 and April 1995.
- Outcomes were compared to a historical cohort using one left ITA and saphenous vein grafts.
Main Results:
- A total of 774 arterial conduits were used across the patient cohort.
- In-hospital and late mortality rates were low at 1.2% and 1.6%, respectively.
- Event-free survival was significantly better in the total arterial group (93.72%) compared to the mixed graft group (85.62%), P = .021.
Conclusions:
- Complete revascularization with three or more arterial conduits is technically feasible.
- This strategy yields low mortality and favorable mid-term event-free survival.
- The study supports the continued use of total arterial grafting for myocardial revascularization.
Abstract:
A complete revascularization with three or more arterial conduits was achieved, giving the patient, if possible, three blood sources from the in situ arterial grafts (skeletonized bilateral internal thoracic arteries [ITAs] and right gastroepiploic artery). If one of these conduits was not available, a radial artery was used, the proximal anastomosis being constructed on an ITA. The inferior epigastric artery was used if a sequential anastomosis was not advisable or to lengthen another arterial graft. With this strategy, 247 patients underwent surgery from October 1991 through April 1995; 774 arterial conduits were used: 244 left ITAs, 187 right ITAs, 159 right gastroepiploic arteries, 114 radial arteries, and 70 inferior epigastric arteries. The in-hospital and late mortality rates were 1.2% (3 patients) and 1.6% (4 patients), respectively. Of the 240 patients alive, 235 (97.9%) are asymptomatic. We compared the 42-month survival and event-free survival curves of these patients with those of an historical cohort of patients who underwent surgery with mixed (1 left ITA and saphenous vein grafts) revascularization. Whereas the survival rate was similar (97.82% +/- 1.11% vs 99.35% +/- 0.65, P = .174), the event-free survival rate was significantly better in the total arterial group (93.72% +/- 2.1 % vs 85.62% +/- 2.84%, P = .021). We conclude that complete revascularization with three or more arterial conduits is technically feasible with a low mortality rate; the mid-term results allow us to continue this strategy of myocardial revascularization.
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