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Updated: Aug 17, 2026

A Neonatal Mouse Spinal Cord Compression Injury Model
Published on: March 27, 2016
Orthopedic aspects of myelodysplasia in children
1Northwestern University Medical School, Chicago, IL, USA.
Abstract:
A review of new developments in spina bifida shows that many cases are preventable by administration of periconceptual folic acid, reducing the relative risk by up to 86%. Currently, however, 50% of women of reproductive age have no folic acid in their usual diet. The Centers for Disease Control as recommended folic acid at 0.4 mg/d for all women anticipating pregnancy. The long-term outcomes of sacral level patients show a surprising decline in adult ambulatory status. Adult ambulatory status in spina bifida is significantly predictive (89% accurate) by two variables: motor level and sitting balance. Studies regarding hip dislocation, foot deformities in thoracic level children, the prevalence of spondylolisthesis, and surgical treatment of kyphosis are also reviewed.
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