Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Laser-evoked potentials: exogenous and endogenous components

R Siedenberg1, R D Treede

  • 1Institute of Physiology, University Hospital Eppendorf, Hamburg, FRG.

Electroencephalography and Clinical Neurophysiology
|May 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Associations of preterm birth and neonatal stress exposure with chronic pain in adulthood - Results from the Gutenberg prematurity study.

Journal of psychosomatic research·2024
Same author

Erratum to "How different experimental models of secondary hyperalgesia change the nociceptive flexion reflex" [Clin. Neurophysiol. 132 (2021) 2989-2995].

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2022
Same author

How different experimental models of secondary hyperalgesia change the nociceptive flexion reflex.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2021
Same author

Modulation of the N13 component of the somatosensory evoked potentials in an experimental model of central sensitization in humans.

Scientific reports·2021
Same author

The Quest for more Research on Painful Diabetic Neuropathy.

Neuroscience·2017
Same author

Treatment of painful radiculopathies with capsaicin 8% cutaneous patch.

Current medical research and opinion·2017
Same journal

Coming to terms with brain waves.

Electroencephalography and clinical neurophysiology·2014
Same journal

Habituation of lower leg stretch responses in Parkinson's disease.

Electroencephalography and clinical neurophysiology·2000
Same journal

Asymmetry of cortical excitability revealed by transcranial stimulation in a patient with focal motor epilepsy and cortical myoclonus.

Electroencephalography and clinical neurophysiology·2000
Same journal

Evoked isometric muscle contractions in myopathies: analysis of pathophysiological properties by different stimulus patterns.

Electroencephalography and clinical neurophysiology·2000
Same journal

Task-related coherence and task-related spectral power changes during sequential finger movements.

Electroencephalography and clinical neurophysiology·2000
Same journal

Electrophysiological studies in mild idiopathic carpal tunnel syndrome.

Electroencephalography and clinical neurophysiology·2000
See all related articles

This study differentiated the physical (exogenous) and cognitive (endogenous) aspects of laser-evoked potentials (LEPs). Findings reveal distinct components, P400 and P570, reflecting stimulus properties and attention-dependent processing, respectively.

Area of Science:

  • Neuroscience
  • Pain Perception
  • Electrophysiology

Background:

  • Laser-evoked potentials (LEPs) are crucial for studying pain processing.
  • Distinguishing exogenous (stimulus-related) and endogenous (cognitive) components of LEPs is essential for accurate interpretation.

Purpose of the Study:

  • To differentiate the exogenous and endogenous components of laser-evoked potentials (LEPs).
  • To characterize the P400 (exogenous) and P570 (endogenous) components of LEPs under various cognitive tasks.

Main Methods:

  • Painful CO2-laser stimuli were applied to the feet of healthy subjects.
  • LEPs were recorded using scalp electrodes under distraction, oddball, and neutral tasks.
  • Analysis focused on peak latency, amplitude, and scalp topography of LEP components.

Related Experiment Videos

Main Results:

  • A task-dependent positivity dominated LEPs, with amplitude increasing with attention.
  • The exogenous P400 component (peak ~400ms, vertex maximum) was identified during distraction.
  • The endogenous P570 component (peak ~570ms, parietal maximum) was observed in oddball tasks and modulated by inter-stimulus interval.

Conclusions:

  • LEPs comprise both exogenous (P400) and endogenous (P570) components.
  • The P400 reflects physical stimulus properties, while P570 represents cognitive processing and attention.
  • Under neutral conditions, LEPs are a superposition of these exogenous and endogenous potentials.