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[Studies on blood traumatization following heart-valve prosthesis]
Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
|March 15, 1977
Summary
Different artificial heart valves cause varying degrees of blood trauma and hemolysis. Beall prostheses caused the most, while Björk-Shirley showed advantages in aortic positions. Paravalvular leakage significantly increased hemolysis.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
- Hematology
Context:
- Cardiac valve interventions, including prostheses implantation, reconstruction, and re-operations for paravalvular leakage, were analyzed.
- A cohort of 47 patients undergoing these procedures was studied.
Purpose:
- To assess blood traumatization and hemolysis levels associated with different artificial heart valve types (Starr-Edwards, Björk-Shiley, Beall).
- To evaluate the impact of paravalvular leakage on hemolysis and the effectiveness of its correction.
Summary:
- Subclinical hemolysis was observed with Starr-Edwards, Björk-Shiley, and Beall prostheses, with Beall causing the highest blood trauma.
- Björk-Shiley valves demonstrated advantages over Starr-Edwards in aortic positions.
- Paravalvular leakage significantly elevated hemolysis parameters, which normalized after successful surgical correction in most cases.
Impact:
- Findings are crucial for selecting and improving artificial heart valve designs.
- Hemolysis parameter assessment is vital for diagnosing paravalvular leakage and monitoring post-repair outcomes.
- This research aids in optimizing patient outcomes following cardiac valve surgery.