Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The pathogenesis of septic shock

S R Crowley1

  • 1Surgical Trauma Intensive Care Unit, Mayo Medical Center, Rochester, MN 55905, USA.

Heart & Lung : the Journal of Critical Care
|March 1, 1996
PubMed
Summary

A new era of septic shock treatment is emerging, focusing on multidrug and immune-modulating therapies to manage the body's inflammatory response to infection. Critical care nurses must stay updated on cellular events and mediators causing septic shock for optimal patient care.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[(Aminomethyl)arloxy]acetic acid esters. A new class of high-ceiling diuretics. 3. Variation in the bridge between the aromatic rings to complete mapping of the receptor.

Journal of medicinal chemistry·1985
Same author

[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 2. Modifications of the oxyacetic side chain.

Journal of medicinal chemistry·1984
Same author

Substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazole-6-carboxylic acids: high-ceiling diuretics with uricosuric activity.

Journal of medicinal chemistry·1984
See all related articles

Area of Science:

  • Critical care medicine
  • Immunology
  • Pathophysiology

Background:

  • Septic shock is a life-threatening condition characterized by a dysregulated inflammatory response to infection.
  • Understanding the cellular mechanisms and inflammatory mediators is crucial for effective treatment.
  • Current treatment paradigms are evolving towards more comprehensive, multidrug approaches.

Purpose of the Study:

  • To review recent advances in understanding the cellular events underlying septic shock.
  • To discuss the role of inflammatory mediators in vasodilation and capillary leak.
  • To highlight the importance of updated knowledge for critical care nurses.

Main Methods:

  • Literature review of cellular events in septic shock.
  • Discussion of hemodynamic characteristics.
  • Analysis of inflammatory mediator actions.

Main Results:

  • Advances in understanding cellular events in septic shock.
  • Identification of key inflammatory mediators causing vasodilation and capillary leak.
  • Emphasis on the need for critical care nurses to integrate new knowledge.

Conclusions:

  • A multidrug approach, including immune and inflammatory modulation, is the future of septic shock treatment.
  • Updated knowledge of septic shock pathophysiology is essential for critical care nurses.
  • Optimal patient care requires understanding symptoms, hemodynamics, and mediator actions.

Related Experiment Videos