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Hydroxymycotrienins A and B, new ansamycin group antibiotics
N Hosokawa1, H Naganawa, M Hamada
1Institute of Microbial Chemistry, Tokyo, Japan.
The Journal of Antibiotics
|May 1, 1996
Abstract:
New ansamycins designated hydroxymycotrienins A and B were isolated from culture broths of Bacillus sp. BMJ958-62F4. The two antibiotics inhibited more strongly the growth of human cervical cancer cell lines of human papilloma virus (HPV) positive than that of HPV negative cell lines. The structures, some biological and biochemical properties are reported.