[Nuclear alterations on organ cultures of human malignant melanomas (author's transl)]

Report on ultrastructurally striking nuclear anomalies in organ cultures obtained from amelanotic and pigmented human melanomas. These nuclear anomalies are more impressive than the nuclear invaginations present in tumours cells of several other malignant growths. Numerous nuclear fragments varying in size and held together by nuclear membrane bands may occur. The karyoplasm of these nuclei reveals nothing unusual no degenerative changes can be found.