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Interstitial cystitis in children

C E Close1, M C Carr, M W Burns

  • 1Division of Pediatric Urology, Children's Hospital and Medical Center, Seattle, Washington, USA.

The Journal of Urology
|August 1, 1996
PubMed
Summary
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Interstitial cystitis (IC), a rare condition in children, presents with bladder pain, urgency, and frequency. Diagnosis is confirmed by cystoscopy, and hydrodistension offers symptom relief, though repeat treatments may be needed.

Area of Science:

  • Pediatric Urology
  • Urology
  • Pediatric Nephrology

Background:

  • Interstitial cystitis (IC) is infrequently documented in pediatric populations.
  • Chronic bladder pain, sensory urgency, and frequency are key symptoms.

Purpose of the Study:

  • To report on the clinical experience with 16 children diagnosed with interstitial cystitis.
  • To highlight the diagnostic criteria and treatment outcomes for pediatric IC.

Main Methods:

  • Retrospective chart review of 20 children with chronic sensory urgency, frequency, and bladder pain.
  • Exclusion of 4 patients due to infection or lack of cystoscopic changes post-hydrodistension.
  • Analysis of clinical presentation, cystoscopic findings, urodynamics, and treatment response.

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Main Results:

  • 16 children diagnosed with IC, with symptom onset between 2-11 years.
  • 88% presented with urinary frequency and sensory urgency; 81% reported pain relieved by voiding.
  • All patients showed glomerulations and terminal hematuria post-hydrodistension; 93% experienced symptom relief, 50% requiring repeat hydrodistension.

Conclusions:

  • Pediatric IC is characterized by bladder pain, frequency, and urgency with specific cystoscopic findings.
  • Hydrodistension is an effective treatment, though recurrence may necessitate repeat procedures.
  • Distinguishing IC from dysfunctional voiding is crucial, as the latter involves involuntary bladder contractions.