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[Tuberculous meningitis. A case with severe ocular complications]
A Beneggi1, P Adamoli, E Bernardini
1Divisione di Pediatria, Ospedale Civile di Sondrio, Italia.
Insights
Tuberculosis meningitis is a severe disease with poor outcomes, especially in advanced stages. Intrathecal therapy for optochiasmatic tuberculomas showed good visual recovery, indicating successful treatment of perichiasmatic lesions.
Area of Science:
- Neurology
- Infectious Diseases
- Ophthalmology
Background:
- Tuberculosis remains a leading infectious cause of death globally, with increasing incidence in both developed and developing nations.
- Tuberculosis meningitis is a severe manifestation, with outcomes heavily dependent on disease stage at presentation.
- Severe cases, particularly those with coma, have a poor prognosis, with complete recovery in only about 20% of pediatric patients.
Abstract:
Tuberculosis in the world is the mean cause of death from single infectious agent. It is reported increase not only in underdeveloped countries but in developed too. Tuberculosis meningitis is a very serious form of tuberculosis. Outcome in tuberculosis meningitis is associated with the stage of the disease at presentation. When the child at presentation is extremely ill with coma the completely recovery is seen only in about 20% of cases. In our case patient had severe ocular complications: optochiasmatic tuberculomas. It is difficult recognize the two forms of tuberculomas intra- and perichiasmatic even with RNM. The good response at intrathecal therapy with recovery of the visus proves the perichiamsatic localitation of tuberculomas.