Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Peutz-Jeghers syndrome]

A Meozzi1, E Tarantino, A Villirillo

  • 1Istituto di Clinica Pediatrica, Università degli Studi, Pisa, Italia.

La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Viscoelastic properties and thermodynamic balance improvement of a hyaluronic acid hydrogel enriched with proline and glycyne.

Journal of biological regulators and homeostatic agents·2019
Same author

Treatment of esophageal perforation in octogenarians: a multicenter study.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2013
Same author

Aarskog-Scott syndrome: clinical update and report of nine novel mutations of the FGD1 gene.

American journal of medical genetics. Part A·2010
Same author

Further delineation of Pitt-Hopkins syndrome: phenotypic and genotypic description of 16 novel patients.

Journal of medical genetics·2008
Same author

Clinical score of 62 Italian patients with Cornelia de Lange syndrome and correlations with the presence and type of NIPBL mutation.

Clinical genetics·2007
Same author

Gastrointestinal surgical emergencies in patients treated for hemathological malignancies.

I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]·2006
Same journal

Beyond lead points: transient small-bowel intussusception in adolescents without structural lesions.

La Pediatria medica e chirurgica : Medical and surgical pediatrics·2026
Same journal

From outreach to ownership: building sustainable paediatric surgical capacity at a secondary hospital in rural Tanzania. A ten-year experience.

La Pediatria medica e chirurgica : Medical and surgical pediatrics·2026
Same journal

Advances in pediatrics: new technologies in clinical practice.

La Pediatria medica e chirurgica : Medical and surgical pediatrics·2026
Same journal

Primary intestinal lymphangiectasia presenting with intussusception in a child.

La Pediatria medica e chirurgica : Medical and surgical pediatrics·2026
Same journal

Prevention and awareness of pool suction-drain injuries in children: two case reports.

La Pediatria medica e chirurgica : Medical and surgical pediatrics·2026
Same journal

Hybrid one-stage Snodgrass-Duckett urethroplasty for severe hypospadias. A five-year institutional experience.

La Pediatria medica e chirurgica : Medical and surgical pediatrics·2026
See all related articles

Peutz-Jeghers syndrome is a rare genetic disorder that increases cancer risk. This review highlights the disease

Area of Science:

  • Medical Genetics
  • Oncology
  • Gastroenterology

Background:

  • Peutz-Jeghers syndrome (PJS) is an autosomal dominant disorder.
  • Characterized by hamartomatous polyps in the gastrointestinal tract and mucocutaneous pigmentation.
  • Associated with a significantly increased lifetime risk of various malignancies.

Observation:

  • Presents a case study of a 13-year-old girl with Peutz-Jeghers syndrome.
  • Reviews the established clinical manifestations and natural progression of PJS.
  • Focuses on the spectrum of complications, particularly the development of cancers.

Findings:

  • Cancer incidence in PJS patients ranges from 22% to 48%.
  • Both gastrointestinal and non-gastrointestinal tumors are observed.

Related Experiment Videos

  • The review synthesizes current data on malignancy occurrence in PJS.

    • Implications:

    • Emphasizes the critical need for robust surveillance protocols in at-risk individuals.
    • Highlights the importance of genetic counseling for PJS patients and families.
    • Informs clinical management strategies to improve outcomes and early detection of cancers.