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Related Experiment Videos

Sustained decrease of blood pressure in psoriatic patients during treatment at the Dead Sea

J Shani1, A P Kushelevsky, M Harari

  • 1Department of Pharmacology, Hebrew University School of Pharmacy, Jerusalem, Israel.

Pharmacological Research
|June 1, 1995
PubMed
Summary

This study found that Dead Sea treatments effectively lowered blood pressure in psoriatic patients, including those with hypertension. High blood pressure is not a contraindication for this psoriasis therapy.

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Area of Science:

  • Dermatology
  • Cardiology
  • Environmental Medicine

Background:

  • Psoriasis is a chronic inflammatory skin condition affecting millions worldwide.
  • Managing comorbidities like hypertension in psoriatic patients is crucial for overall health.
  • The Dead Sea is a unique natural environment utilized for therapeutic purposes.

Purpose of the Study:

  • To investigate the effect of a 4-week Dead Sea treatment on blood pressure in psoriatic patients.
  • To determine if pre-existing hypertension contraindicates Dead Sea psoriasis therapy.
  • To analyze blood pressure changes in psoriatic patients with varying hypertensive statuses.

Main Methods:

  • Monitoring systolic and diastolic blood pressure in 1366 psoriatic patients over 4 weeks.
  • Categorizing patients into three groups: on antihypertensive medication, untreated hypertension (diastolic BP ≥ 90 mmHg), and normal blood pressure (diastolic BP < 90 mmHg).

Related Experiment Videos

  • Utilizing paired t-tests to analyze blood pressure changes from baseline.

    • Main Results:

    • Significant average reductions in systolic blood pressure (22 mmHg) and diastolic blood pressure (11-16 mmHg) were observed in hypertensive groups.
    • Blood pressure reductions were noted within 2 days of arrival and stabilized after 2 weeks.
    • Normotensive psoriatic patients also showed a similar decrease in systolic blood pressure.

    Conclusions:

    • Dead Sea climatotherapy can lead to significant reductions in blood pressure among psoriatic patients.
    • Elevated blood pressure is not a contraindication for undergoing psoriasis treatment at the Dead Sea.
    • The therapeutic environment of the Dead Sea may offer cardiovascular benefits alongside dermatological improvements.