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[Evaluation of bones using quantitative ultrasonography]

M A Krieg1, D Thiébaud, M Landry

  • 1Département de médecine interne, Service A, CHUV, Lausanne.

Schweizerische Medizinische Wochenschrift
|February 3, 1996
PubMed
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Ultrasound bone measurement, using bone ultrasound attenuation (BUA) and speed of sound (SOS), shows high correlation with DXA scans for osteoporosis screening in postmenopausal women. This non-irradiating method is reliable for assessing bone health.

Area of Science:

  • Medical Imaging
  • Biophysics
  • Osteoporosis Research

Background:

  • Ultrasound bone evaluation offers a non-ionizing, portable alternative to traditional methods.
  • Bone ultrasound measurements include bone ultrasound attenuation (BUA) and speed of sound (SOS).
  • The calcaneus is a common site for ultrasound bone assessment.

Purpose of the Study:

  • To evaluate the reproducibility of ultrasound bone measurements (BUA and SOS) in healthy volunteers.
  • To determine the correlation between ultrasound bone measurements and dual-energy X-ray absorptiometry (DXA) in postmenopausal women.
  • To validate ultrasound as a screening tool for osteoporosis in a clinical setting.

Main Methods:

  • Utilized the Achilles ultrasound device (Lunar) for bone measurements.

Related Experiment Videos

  • Assessed reproducibility in healthy volunteers.
  • Correlated ultrasound findings with DXA results (Hologic QDR 2000) in 57 postmenopausal women (mean age 59).

    • Main Results:

    • Ultrasound measurement reproducibility showed coefficients of variation of 1.8% for BUA and 0.3% for SOS.
    • Significant correlations (p < 0.001) were found between ultrasound and DXA at the lumbar spine, femoral neck, and calcaneus.
    • The strongest correlation (r > 0.8) was observed when ultrasound and DXA were applied to the same site (calcaneus).
    • Low ultrasound values (BUA < 100 dB/MHz, SOS < 1495 m/s) strongly suggested osteoporosis.

    Conclusions:

    • Ultrasound bone measurement is a reproducible and reliable method for assessing bone status.
    • Ultrasound shows significant correlation with DXA, particularly at the calcaneus, supporting its use in osteoporosis screening.
    • Ultrasound parameters can effectively differentiate between osteoporotic and non-osteoporotic individuals, warranting further investigation into fracture risk assessment.