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Updated: Jul 26, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Published on: October 12, 2018

Surgery and human immunodeficiency virus-1 infection

C Wastell¹, D Corless, N Keeling

¹Academic Surgical Unit, Chelsea & Westminster Hospital, London, UK.

American Journal of Surgery

|July 1, 1996

Summary

Surgical management of patients with Acquired Immunodeficiency Syndrome (AIDS) requires careful consideration. Specific disease patterns in AIDS patients necessitate a dedicated surgical team for optimal outcomes.

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Area of Science:

Surgery
Infectious Diseases
Immunology

Background:

Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) remain significant global health challenges.
Patients with HIV/AIDS frequently require surgical intervention, posing unique management considerations.

Purpose of the Study:

To review the surgical management of patients with AIDS.
To highlight safety considerations and specific disease patterns in this patient population.

Main Methods:

A retrospective review of patient case notes was conducted over a two-year period.
Data analysis focused on invasive procedures, venous access, anorectal problems, and major surgeries.

Main Results:

A total of 237 patients underwent invasive procedures.
Venous access procedures were most common (145 procedures in 100 patients).
Anorectal issues affected 69 patients, and 26 patients (30 procedures) underwent major surgery.

Conclusions:

The surgical management of AIDS patients requires a safety-focused approach.
Recognizing specific disease patterns is crucial for effective treatment.
A dedicated multidisciplinary team is essential for optimal care of these patients.