Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fourier transform spectroscopic imaging using an infrared focal-plane array detector

E N Lewis1, P J Treado, R C Reeder

  • 1Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Analytical Chemistry
|October 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel combination of DLS-optical microrheology and low frequency Raman spectroscopy to reveal underlying biopolymer self-assembly and gelation mechanisms.

The Journal of chemical physics·2014
Same author

Infrared Spectroscopic Imaging of the Biochemical Modifications Induced in the Cerebellum of the Niemann-Pick type C Mouse.

Journal of biomedical optics·2012
Same author

Peer reviewed: Raman chemical imaging spectroscopy.

Analytical chemistry·2011
Same author

Use of vibrational spectroscopy in defining the role of clathrin in coated vesicle formation.

Biophysical journal·2009
Same author

Measuring the effects of topical moisturizers on changes in stratum corneum thickness, water gradients and hydration in vivo.

The British journal of dermatology·2008
Same author

Conformational differences in protein disulfide linkages between normal hair and hair from subjects with trichothiodystrophy: a quantitative analysis by Raman microspectroscopy.

Biopolymers·2006

A new mid-infrared spectroscopic chemical imaging technique uses step-scan interferometry and focal-plane array detectors for rapid, high-definition chemical analysis of materials. This powerful method enables simultaneous spectral and spatial data collection for advanced material characterization.

Area of Science:

  • Chemical imaging
  • Spectroscopy
  • Material Science

Background:

  • Infrared (IR) spectroscopy is vital for molecular analysis.
  • Chemical imaging combines spectroscopy with visualization for material characterization.
  • Heterogeneous materials require non-invasive molecular characterization techniques.

Purpose of the Study:

  • To describe a novel mid-infrared spectroscopic chemical imaging technique.
  • To demonstrate its capability for high-definition and rapid chemical analysis.
  • To present the principles, instrument design, and results of this new method.

Main Methods:

  • Utilizes step-scan Fourier transform Michelson interferometry.
  • Employs indium antimonide focal-plane array (FPA) detectors for image detection.

Related Experiment Videos

  • Combines multiplex/multichannel advantage for simultaneous spectral and spatial data acquisition.
  • Main Results:

    • Achieved high-definition mid-infrared chemical imaging with high fidelity.
    • Demonstrated rapid spectral image acquisition, requiring only seconds.
    • Enabled simultaneous collection of spectra from all pixels and all spectral frequencies.

    Conclusions:

    • The described technique represents a significant advancement in infrared chemical imaging analysis.
    • This method offers broad applicability for non-invasive, molecular characterization of heterogeneous materials.
    • The rapid, high-resolution capabilities have wide-ranging implications for chemical analysis and material science.