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[Giant mesenteric fibromatosis: a case report]
F Cianchi1, G Perigli, F Pucciani
1Università degli Studi di Firenze, Clinica Chirurgica Generale e Terapia Chirurgica.
Annali Italiani Di Chirurgia
|July 1, 1995
Summary
Mesenteric fibromatosis, a rare fibroblastic tumor, can grow extensively but does not metastasize. Wide surgical excision is the primary treatment to prevent recurrence, with limited success from radiotherapy.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Fibromatoses are infiltrative fibroblastic proliferations with a high recurrence rate but no metastatic potential.
- Mesenteric fibromatosis, originating from the small bowel mesentery, is a rare entity, occasionally associated with Gardner's syndrome.
Observation:
- A case of massive mesenteric fibromatosis (12 kg, 50 cm diameter) in a 52-year-old male without Gardner's syndrome is presented.
- The neoplasm extensively occupied the abdominal cavity.
Findings:
- Histological examination revealed moderate cellularity, absence of nuclear pleomorphism, and no mitotic figures, confirming a benign nature and ruling out malignancy.
- Surgical removal is the only effective treatment for mesenteric fibromatosis.
Implications:
- Wide surgical excision is crucial for preventing local recurrence of mesenteric fibromatosis.
- External radiotherapy has shown limited efficacy, while anti-inflammatory drugs are being explored as a management option.