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[Hypopigmented mycosis fungoides]

C Robert¹, Z Bahlouli, P Chemaly

¹Clinique des Maladies cutanées, Hôpital Saint-Louis, Paris.

Annales De Dermatologie Et De Venereologie

|January 1, 1995

Summary

Hypopigmented mycosis fungoides, a rare skin condition in Black individuals, presents as hypopigmented macules. Photochemotherapy with PUVA (psoralen plus ultraviolet A) effectively treated these lesions.

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Area of Science:

Dermatology
Oncology

Background:

Mycosis fungoides can present as isolated hypopigmented skin areas, a rare form predominantly observed in individuals of Black African descent.
This specific clinical presentation often leads to delayed diagnosis due to its initial misclassification as benign conditions like pityriasis alba or versicolor.

Observation:

A 28-year-old woman from Mali presented with widespread, non-infiltrated, hypopigmented, and slightly scaly macules over 10 years.
Pathology confirmed epidermotropic lymphocyte infiltration, indicative of mycosis fungoides.

Findings:

Hypopigmented mycosis fungoides is typically diagnosed late, often mistaken for benign conditions like pityriasis alba.
Photochemotherapy (PUVA) demonstrated rapid regression of lesions in the reported case.

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Implications:

Prompt recognition and diagnosis of hypopigmented mycosis fungoides are essential for effective management.
PUVA therapy appears to be a promising treatment option for this rare condition.