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Oral hyposensitization of children with pollinosis or house-dust asthma
Insights
Oral hyposensitization is a safe and effective treatment for respiratory allergies in children. This method shows results comparable to traditional treatments for conditions like pollinosis and house-dust asthma.
Area of Science:
- Pediatric Allergy and Immunology
- Immunotherapy
Background:
- Oral hyposensitization has a 25-year track record of safety and efficacy.
- It is a viable treatment option for specific respiratory allergies in children aged 10-12 years.
Purpose of the Study:
- To evaluate the effectiveness and safety of oral hyposensitization for pediatric respiratory allergies.
- To describe methods for preparing and administering oral extracts for house-dust asthma.
Main Methods:
- Utilized aqueous extracts or pollen powder for pollinosis treatment.
- Employed commercially available or patient-specific house-dust extracts for asthma treatment.
- Detailed procedures for house-dust sample collection, testing, and extract preparation.
Main Results:
- Achieved results comparable to subcutaneous hyposensitization after two treatment courses for pollinosis.
- Demonstrated good long-term outcomes for children with house-dust asthma undergoing oral hyposensitization.
Conclusions:
- Oral hyposensitization is a proven, safe, and effective therapeutic strategy for pediatric respiratory allergies.
- The described methods facilitate the application of oral hyposensitization, particularly for house-dust-induced asthma.
Abstract:
25 years of experience have proven oral hyposensitization to be an effective and safe method for specific treatment of respiratory allergies in children up to the age of 10-12 years. For pollinosis aqueous extracts or pollen powder are used. Results after at least two cures are comparable to those observed after subcutaneous hyposensitization. In house-dust asthma oral hyposensitization is performed either with commercially available extracts or with extracts prepared from the patient's own house-dust. The way to collect such dust samples, their use in testing and the preparation of extracts from it are described. Long-term results with oral hyposensitization of children with house-dust asthma are good.