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Synthesis and antiinflammatory activity of 2,3-dihydro-1,4-benzodioxin methyl carboxylic acids
M T Vázquez1, G Rosell, M D Pujol
1Laboratori de Química Farmacèutica, Facultat de Farmàcia, Universitat de Barcelona, Spain.
Farmaco (Societa Chimica Italiana : 1989)
|March 1, 1996
Abstract:
Synthesis and antiinflammatory properties of new carboxylic acids containing the 2,3-dihydro-1,4-benzodioxin subunit are described. The 2-(2,3-dihydro-1, 4-benzodioxin-6-yl)acetic acid was of comparable potency to Ibuprofen, in carrageenan induced rat paw edema assay.