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Related Experiment Videos

Hepatic sensitivity to imipramine

G A Weaver, D Pavlinac, J S Davis

    The American Journal of Digestive Diseases
    |June 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    This case study documents a severe liver reaction to imipramine, confirmed by a liver biopsy and drug challenge. The reaction may be due to hypersensitivity or toxic metabolite induction.

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    Area of Science:

    • Hepatology
    • Clinical Pharmacology
    • Toxicology

    Background:

    • Imipramine is a tricyclic antidepressant with known potential for adverse drug reactions.
    • Hepatic reactions, though uncommon, can be a serious side effect of antidepressant medications.