Long-term results in the treatment of regional ileitis with coherin

Nineteen patients with severe symptoms of ileitis, not responsive to other forms of therapy, have been treated with coherin, a peptide isolated from bovine posterior pituitary glands. This study encompasses observations over a total of 50-patient years. tcoherin has proven efficacious by three criteria: As a result of coherin treatment those patients receiving steroids could either eliminate them or reduce the dosage to safe levels. A significant number of patients whose symptoms have been controlled by coherin have demonstrated their therapeutic dependence on coherin for relief of symptoms by multiple unsuccessful attempts to discontinue treatment over a long period of time. Diarrhea, in patients with ileitis symptoms, is effectively controlled by coherin therapy on a long-term basis.