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Sphincter of Oddi

J Toouli1

  • 1Department of Surgery, Flinders Medical Centre, Bedford Park, Adelaide, South Australia.

The Gastroenterologist
|March 1, 1996
PubMed
Summary
This summary is machine-generated.

Sphincter of Oddi dysfunction, a motility disorder, can cause biliary pain or pancreatitis. Surgical division of the sphincter effectively cures symptoms in over 70% of patients with stenosis.

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Area of Science:

  • Gastroenterology and Hepatobiliary Surgery
  • Digestive System Physiology
  • Surgical Interventions

Background:

  • The Sphincter of Oddi, described over a century ago, has had its anatomy and independent function elucidated.
  • Modern manometry has defined its motor activity and identified motility abnormalities linked to specific clinical conditions.

Purpose of the Study:

  • To describe Sphincter of Oddi dysfunction (SOD) as a motility disorder.
  • To review clinical findings regarding the efficacy of sphincter division for symptom relief in patients with SOD.

Main Methods:

  • Utilized modern manometric techniques to assess sphincter motor activity and identify motility disorders.
  • Analyzed clinical studies focusing on patients with recurrent biliary-type pain or idiopathic recurrent pancreatitis.

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  • Evaluated outcomes following surgical division of the sphincter.

    • Main Results:

    • Sphincter of Oddi dysfunction (SOD) is characterized by motility disorders of the sphincter.
    • Surgical division of the sphincter achieved symptom cure in over 70% of patients diagnosed with manometrically determined stenosis.
    • Specific surgical approaches are indicated for biliary-type pain versus idiopathic recurrent pancreatitis.

    Conclusions:

    • Sphincter of Oddi dysfunction is a recognized clinical entity.
    • Sphincter division is a highly effective treatment for patients with manometrically confirmed SOD and associated symptoms.
    • Tailored surgical division is essential for optimal outcomes in different patient populations.