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Related Concept Videos

The Mechanics of (Poro-)Elastic Contractile Actomyosin Networks As a Model System of the Cell Cytoskeleton08:50

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In this work, an in vitro reconstitution approach is employed to study the poroelasticity of actomyosin gels under controlled conditions. The dynamics of the actomyosin gel and the embedded solvent are quantified, through which the network poroelasticity is demonstrated. We also discuss the experimental challenges, common pitfalls, and relevance to cell cytoskeleton...
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Related Experiment Video

Updated: Jan 12, 2026

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix
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Treating the agitated Alzheimer patient

E M Zayas1, G T Grossberg

  • 1Department of Psychiatry and Human Behavior, Saint Louis University School of Medicine, MO 63104, USA.

The Journal of Clinical Psychiatry
|January 1, 1996
PubMed
Summary

Agitation is common in dementia patients, affecting over half of those in nursing homes and outpatient settings. This review outlines strategies for evaluating and treating agitation in dementia, aligning with Omnibus Budget Reconciliation Act regulations.

Area of Science:

  • Geriatric Medicine
  • Neurology
  • Psychiatry

Background:

  • Dementia encompasses cognitive, psychiatric, and behavioral changes.
  • Behavioral disturbances, including agitation, are prevalent in dementia patients, affecting a significant percentage of nursing home residents and outpatients.
  • Regulatory requirements mandate physician familiarity with alternative treatments for behavioral disturbances.

Purpose of the Study:

  • To review and present evidence-based strategies for the evaluation and treatment of agitation in patients with dementia.
  • To provide physicians with a framework for managing agitation in accordance with regulatory guidelines.

Main Methods:

  • Literature review of studies on dementia, behavioral disturbances, and agitation management.
  • Synthesis of current clinical guidelines and research findings.

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  • Analysis of treatment options, including non-pharmacological and pharmacological interventions.

    • Main Results:

    • Agitation is a frequent and challenging behavioral disturbance in dementia.
    • A comprehensive evaluation is crucial for identifying underlying causes of agitation.
    • A multimodal treatment approach, often starting with non-pharmacological strategies, is recommended.

    Conclusions:

    • Effective management of agitation in dementia requires a thorough understanding of the syndrome and available treatment options.
    • Physicians must be aware of and adhere to regulatory requirements, such as those from the Omnibus Budget Reconciliation Act, when developing treatment plans.
    • This review provides a valuable resource for clinicians managing agitated dementia patients.