Oral infection of mice with trophozoites of Giardia muris
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Updated: Aug 15, 2026

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Trichuris muris Infection: A Model of Type 2 Immunity and Inflammation in the Gut
Published on: May 24, 2011
Abstract:
Giardia muris has been maintained for years in the mouse by administering by gavage 10,000 trophozoites taken from the small intestine of infected mice. Despite the growth of numerous protozoa in the intestine, absorption of tetracycline hydrochloride in infected mice was not changed to a statistically significant extent, as blood drug levels increased only slightly: behavior was similarly unaffected. Reasons for the apparent lack of virulence of this strain are discussed.
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