Effect of buprenorphine on the ventilatory response to carbon dioxide
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Anaesthesia and Intensive Care
|May 1, 1977
Abstract:
Buprenorphine is a potent synthetic opioid-partial antagonist analgesic drug currently under clinical trial. When administered intravenously to human volunteers buprenorphine produced a significant depression of the ventilatory response to carbon dioxide stimulus for a period in excess of six hours.