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Hostility predicts restenosis after percutaneous transluminal coronary angioplasty

M Goodman1, J Quigley, G Moran

  • 1Department of Psychiatry and Behavioral Medicine, Union Memorial Hospital, Baltimore, Maryland, USA.

Mayo Clinic Proceedings
|August 1, 1996
PubMed

Insights

High hostility, a component of Type A behavior, significantly increases the risk of restenosis after percutaneous transluminal coronary angioplasty (PTCA). Modifying this behavior may reduce cardiac events and restenosis rates in patients.

Area of Science:

  • Cardiology
  • Behavioral Medicine
  • Psychosocial Factors in Cardiovascular Disease

Background:

  • Type A behavior pattern is linked to cardiovascular disease.
  • The
  • total (potential for) hostility
  • component specifically is examined.
  • Restenosis after percutaneous transluminal coronary angioplasty (PTCA) is a significant clinical concern.

Purpose of the Study:

  • To assess the predictive value of the
  • total (potential for) hostility
  • component of Type A behavior for restenosis post-PTCA.
  • To determine if hostility scores correlate with the extent of restenosis.

Main Methods:

  • A structured interview assessed Type A behavior in 41 patients scheduled for or having undergone PTCA.
  • Patients were monitored for restenosis, with 15 (36.6%) experiencing it.
  • Logistic regression analyzed the relationship between hostility scores and restenosis.

Main Results:

  • Patients with high
  • total (potential for) hostility
  • scores were 2.5 times more likely to develop restenosis.
  • Hostility scores independently predicted restenosis, even after adjusting for gender and race.
  • Higher hostility scores were associated with restenosis in a greater number of arteries.

Conclusions:

  • This study is the first to link Type A
  • total (potential for) hostility
  • to increased restenosis risk after PTCA.
  • Behavior modification targeting hostility may reduce recurrent cardiac events.
  • A program for behavior modification in patients with persistent restenosis has been implemented.
Abstract

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