Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Hypertension: a personal odyssey

The Mount Sinai Journal of Medicine, New York

|May 1, 1996

Summary

This summary is machine-generated.

This research details a personal journey in hypertension, from animal studies to human vascular disease. It highlights advancements in understanding and treating essential hypertension, including its genetic and environmental factors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Histamine-releasing activity and binding to the FcepsilonRI alpha human mast cell receptor subunit of mast cell degranulating peptide analogues with alanine substitutions.

Journal of medicinal chemistry·2003

Same author

Mast cell degranulating peptide binds to RBL-2H3 mast cell receptors and inhibits IgE binding.

Peptides·2002

Same author

Intimal tissue factor activity is released from the arterial wall after injury.

Thrombosis and haemostasis·2000

Same author

Nucleolar localization of BRCA1 protein in human breast cancer.

International journal of oncology·1998

Same author

Tissue factor in the pathogenesis of atherosclerosis.

Thrombosis and haemostasis·1997

Same author

Tissue factor is rapidly induced in arterial smooth muscle after balloon injury.

The Journal of clinical investigation·1993

Same journal

Farewell message from Penny A. Asbell, MD, FACS, MBA, Editor-in-Chief of the Mount Sinai Journal of Medicine.

The Mount Sinai journal of medicine, New York·2012

Same journal

Minority undergraduate programs intended to increase participation in biomedical careers.

The Mount Sinai journal of medicine, New York·2012

Same journal

Future of electronic health records: implications for decision support.

The Mount Sinai journal of medicine, New York·2012

Same journal

AA amyloidosis: Mount Sinai experience, 1997-2012.

The Mount Sinai journal of medicine, New York·2012

Same journal

Amyloid neuropathies.

The Mount Sinai journal of medicine, New York·2012

Same journal

Should your family history of coronary heart disease scare you?

The Mount Sinai journal of medicine, New York·2012

See all related articles

Area of Science:

Cardiology and Nephrology
Vascular Biology
Hypertension Research

Background:

Personal research journey at Mount Sinai Hospital and Medical School.
Initial studies on animal hearts, kidneys, and lungs.
Exploration of finger clubbing, hypertrophic osteoarthropathy, and myocardial infarction.

Discussion:

Focus shifted to vascular resistance and reactivity in hypertension and vascular diseases.
Investigation and treatment of specific hypertension causes.
Development of diagnostic and therapeutic strategies for "essential" hypertension.

Key Insights:

Establishment of a dedicated hypertension clinic and laboratory.
Improved definition of hereditary and environmental factors in essential hypertension.

Related Experiment Videos

Insights from spontaneously hypertensive rat models, though human relevance is debated.

Outlook:

Basic research on uterine and vascular smooth muscle physiology and molecular biology.
Understanding complexities of restenosis after angioplasty, arteriosclerosis, and left ventricular hypertrophy.
Acknowledging the collaborative nature of scientific progress in hypertension research.