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Updated: Aug 11, 2026
06:55
Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
[Squamous esophageal papillomas]
K Vandenborre1, L Rutgeerts, G Ghillebert
1Afd. Gastro-enterologie, Heilig Hart Ziekenhuis, Roeselare, België.
Nederlands Tijdschrift Voor Geneeskunde
|May 4, 1996
Summary
Human papilloma virus (HPV) was detected in three esophageal squamous papilloma cases. These benign tumors, though rare, warrant preventive removal due to potential malignant transformation.
Area of Science:
- Gastroenterology
- Oncology
- Virology
Background:
- Esophageal squamous papillomas are rare, benign tumors with unclear pathogenesis.
- Potential etiological factors include local irritation and human papilloma virus (HPV).
Observation:
- Three patients (37, 58, 68 years) incidentally presented with distal esophageal papillomatous lesions.
- Microscopic examination revealed squamous papilloma with parakeratosis; two patients showed poikilocytosis, suggesting HPV infection.
Findings:
- Human papilloma virus (HPV) was indicated as a causative agent in esophageal squamous papillomas.
- The presence of viral antigen or DNA has been demonstrated in similar studies.
Implications:
- Esophageal squamous papillomas, despite being benign, carry a risk of malignant transformation.
- Preventive endoscopic removal is recommended for these lesions.
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